彭棋

发布日期:2025-02-28浏览次数:


彭棋,男,博士/博士后,副教授。2023年引进至生物科学与工程学院从事教学科研工作。主持国家自然科学基金及江西省杰出青年基金等省部级项目共5项。以主要成员身份参与国家重点研发计划及国家自然科学基金面上等多项。研究方向为猪肠道冠状病毒的反向遗传学体系、冠状病毒致病机制和冠状病毒跨物种传播的研究。近年来以第一作者或通讯作者(含共同)在Nature Communications、mBio和Journal of Virology等期刊发表科研论文20余篇,申请/授权发明专利2项。

工作经历:

2023/12-至今,江西农业大学,副教授

2023/1 - 2023/11,江西农业大学,讲师

2020/12 – 2022/12,江苏省农业科学院,博士后

代表性研究成果(#共同第一作者,*通讯作者): 

(1)Weiwei Ji#, Qi Peng#, Xueqiong Fang, Zehou Li, Yaxin Li, Cunfa Xu, Shuqing Zhao, Jizong Li, Rong Chen, Guoxiang Mo, Zhanyong Wei, Ying Xu*, Bin Li*, Shuijun Zhang*. Structures of a deltacoronavirus spike protein bound to porcine and human receptors. Nature Communications, 2022, 13:1467 

(2)Zhang N, Xu Y, Chen Y, Ma M, Lai W, Zhong S, Cai G, Wang T, Li B, Peng Q*, Jiang H*. DEAD-box RNA helicase 21 interacts with the nucleocapsid protein and inhibits porcine deltacoronavirus infection through upregulation of interferon responses. Journal of Virology. 2026 Sep 30:e0116926. doi: 10.1128/jvi.01169-26.

(3)Jiang H, Lu B, Chu Y, Ma M, Zhang N, Xu Y, Chen Y, Xiao Q, Wang T, Peng Q*. Susceptibility of Cell Lines from Different Species to Porcine Deltacoronavirus. Viruses. 2026 Jul 15;18(7):776. doi: 10.3390/v18070776.

(4)Shiyu Liu, Gege Zhang, Jingyuan Xie, Boshui Yuan, Weilu Guo, Yunchuan Li, Rongli Guo, Min Sun, Mi Hu, Yongxiang Zhao, Fei Liu*, Qi Peng*, Bin Li*, Baochao Fan*. Evasion of humoral immune responses by a key mutational region of the S2 subunit in PEDV variants. mBio, 2026 Apr 8;17(4):e0002626. doi: 10.1128/mbio.00026-26

(5)Peng Q* and Kong L*, Editorial: Advancements and challenges in Mpox research. Frontiers in Microbiology. 2026,17:1791735. doi: 10.3389/fmicb.2026.1791735.

(6)Qi Peng #, Baochao Fan #, Xu Song #, Wenlong He, Chuanhong Wang, Yongxiang Zhao, Weilu Guo, Xue Zhang, Shiyu Liu, Jie Gao, Kemang Li, Baotai Zhang, Jinzhu Zhou, Yunchuan Li, Rongli Guo, Bin Li. Genetic signatures associated with the virulence of porcine epidemic diarrhea virus AH2012/12. Journal of Virology. 2023 Sep 21; e0106323.

(7)Hui Jiang, Mengle Jia, Jiaqi Xiong, Changrun Zhao, Ting Wang, Lingbao Kong, Qi Peng*. The network interactions between the porcine deltacoronavirus nucleocapsid protein and host cellular proteins. Veterinary Microbiology. 2024 Aug 17:298:110225.

(8)Wenlong He#, Qi Peng#, Jizong Li#, Jin Huang, Xuhang Cai, Siyuan Li, Baotai Zhang, Li Xiao, Jie Gao, Chuanhong Wang, Jiali Qian, Laqiang Gu, Rui Wang, Xuechao Tang, Kemang Li, Xu Song, Jinzhu Zhou, Mingjun Zhu, Bin Li*. Attenuation of a highly pathogenic porcine deltacoronavirus strain CZ2020 by serial passage in vitro, Transboundary and Emerging Diseases, 2023. https://doi.org/10.1155/2023/2830485.

(9)Hui Jiang, Ting Wang, Lingbao Kong*, Bin Li*, Qi Peng*. Reverse genetics systems for emerging and re-emerging swine coronaviruses and applications. Viruses, 2023, 15, 2003. https://doi.org/10.3390/v15102003.

(10)Baochao Fan#, Qi Peng#, Shiying Song, Danyi Shi, Xue Zhang, Weilu Guo, Yunchuan Li, Jinzhu Zhou, Xuejiao Zhu, Yongxiang Zhao, Rongli Guo, Kongwang He, Huiying Fan, Siyuan Ding, and Bin Li*. Nonstructural protein 1 of variant PEDV plays a key role in escaping replication restriction by complement C3. Journal of Virology. 2022, Aug 29; e0102422.

(11)Qi Peng#, Xue Zhang#, Baochao Fan, Yunchuan Li, Shuqing Zhao, Weilu Guo, Wenlong He, Yongxiang Zhao, Yanxiu Ni, Maojun Liu, Rongmei Fei*, Bin Li*. Evaluation of the transcriptional regulatory efficacy of transcription regulatory sequences of porcine epidemic diarrhea virus. Veterinary Microbiology, 2022, 267: 109376.

(12)Qi Peng, Xue Zhang, Jizong Li, Wenlong He, Baochao Fan, Yanxiu Ni, Maojun Liu, Bin Li*, Comprehensive analysis of codon usage patterns of porcine deltacoronavirus and its host adaptability. Transboundary and Emerging Diseases, 2022, 69(5), e2443-e2455. 

(13)Qi Peng, Liurong Fang, Zhen Ding, Dang Wang, Guiqing Peng, Shaobo Xiao*. Rapid manipulation of the porcine epidemic diarrhea virus genome by CRISPR/Cas9 technology. Journal of Virological Methods, 2020, 276: 113772.

(14)Gege Zhang#, Qi Peng#, Shiyu Liu, Baochao Fan, Chuanhong Wang, Xu Song, Qiuxia Cao, Chengcheng Li, Hong Xu, Hongting Lu, Meiying Bao, Shanshan Yang, Yunchuan Li, Jiaxiang Wang*, Bin Li*. Virus Research, 2024, 345:199381.

(15)Li M, Xiong J, Zhou H, Liu J, Wang C, Jia M, Wang Y, Zhang N, Chen Y, Zhong T, Zhang Z, Li R, Zhang Y, Guo Y, Peng Q*, Kong L*. Transcriptomic and Proteomic Analysis of Monkeypox Virus A5L-Expressing HEK293T Cells. International Journal of Molecular Sciences. 2025 Jan 5;26(1):398. doi: 10.3390/ijms26010398.

(16)彭棋,张雪,赫文龙,范宝超,王丹丹,刘茂军,李彬*.猪流行性腹泻病毒G2a变异株CH-HK-2021的分离鉴定及其遗传进化分析. 南方农业学报. 2022. 53(8):2077-2087.

(17)熊嘉琦,贾梦乐,杨领弟,王毅豪,孙静婷,王婷,黎美凤,孔令保*,彭棋*. 猴痘病毒A5L蛋白的原核表达及其免疫原性评价.中国畜牧兽医. 2024,51(01).

(18)贾梦乐,熊嘉琦,杨领弟,王毅豪,孙静婷,王婷,黎美凤,孔令保*,彭棋*. 猴痘病毒E2L蛋白的表达、纯化及免疫原性评价. 南方农业学报. 2023.

(19)王辰怡, 傅威, 李若铭, 陈佳佳, 李名志, 夏晓锦, 翁雅萍, 孔令保, 彭棋*, 王婷*. 猪繁殖与呼吸综合征病毒Nsp10蛋白多克隆抗体制备及其免疫原性分析[J]. 南方农业学报, 2025, 56 (10): 3241-3249.

(20)陈燕英, 张楠楠, 马明月, 徐艳艳, 张雨欣, 宋娟萍, 孔令保, 王婷, 彭棋, 姜慧*.猪δ冠状病毒N蛋白单克隆抗体制备及其生物学特性鉴定[J/OL].南方农业学报,1-13[2026-10-02].https://link.cnki.net/urlid/45.1381.s.20260325.1634.004.

主持科研/教学项目情况:

(1)国家自然科学基金青年项目C类(2022)

(2)国家自然科学基金地区项目(2025)

(3)江西省杰出青年基金项目(2024)

(4)中国博士后科学基金面上项目(2022)

(5)江西省自然科学基金青年项目(2023)

(6)江西农业大学教改课题(2025)

发明专利

1. 抗猪流行性腹泻病毒的药物组合物及其制备方法和应用. 胡屹屹; 李彬; 李运川; 彭棋; 范宝超; 王丹丹; 祝昊丹; 倪艳秀; 周俊明; 温立斌; 郭容利. 中国专利,2023-10-27,CN116059276B。

2. 一种高效快速构建猪肠道冠状病毒重组病毒的方法. 肖少波; 方六荣; 彭棋; 王荡; 方谱县; 周艳荣; 刘康. 2019-10-15,CN110331171A。