王园园，浙江大学农学博士，中共党员，讲师（校聘教授），山东曹县人。主持中国博士后科学基金项目1项，参与国家自然科学基金项目1项。研究成果发表在Advanced Science、Food Frontiers、Poultry Science、Animal等权威杂志，发表SCI论文20余篇，其中以第一作者发表SCI论文12篇。申请国家发明专利8项，其中授权2项。
联系方式E-mail:wangyuanyuan@jxau.edu.cn
主要研究方向：
肠道微生态与宿主健康、胞外囊泡的作用机制解析与转化应用、益生菌与肠道干细胞调控。
教育经历：
2019-2023，浙江大学，博士
2015-2018，浙江大学，硕士
2011-2015，聊城大学，学士
工作经历：
2026.07 - 至今，江西农业大学，讲师
2023.07 - 2026.05，浙江大学/浙江省人民医院，联合培养博士后
主持课题：
（1）金银花外泌体样纳米囊泡ath-miRNA8175_L-2通过调控Akkermansia muciniphila丰度介导杯状细胞改善黏液屏障缓解炎症性肠病的机制研究，中国博士后科学基金面上资助，8万元，编号：2024M752099，主持（已结题）。
主要发表论文：
1. Wang YY, Zhou YH, Wu QY, et al. Honeysuckle-Derived Nanovesicles Regulate Gut Microbiota for the Treatment of Inflammatory Bowel Disease. Advanced Science, 2025, 12: e05208. (IF=15.6，中科院1区，Top期刊，第一作者)
2. Wang YY, Zeng Y, Liu GY, et al. Rosa roxburghii-derived exosome-like nanovesicles alleviate ulcerative colitis based on Th17/Treg immune balance and gut microbiota modulation. Food Frontiers, 2026. (IF=8.6，中科院1区，Top期刊，第一作者)
3. Wang YY, Xu YB, Cao GT, et al. Bacillus subtilis DSM29784 Attenuates Clostridium perfringens-induced Intestinal Damage of Broilers by Modulating Intestinal Microbiota and the Metabolome. Frontiers in Microbiology, 2023, 14: 1138903. (IF=5.2，中科院2区，第一作者)
4. Wang YY, Wang BK, Zhan XA, et al. Effects of glucose oxidase and its combination with B. amyloliquefaciens SC06 on intestinal microbiota, immune response and antioxidative capacity in broilers. Animal, 2022, 16: 100473. (IF=4.2，中科院1区，Top期刊，第一作者)
5. Wang YY, Zhang L, Xu YB, et al. Impact of Maternal and Offspring Dietary Zn Supplementation on Growth Performance and Antioxidant and Immune Function of Offspring Broilers. Antioxidants, 2022, 11: 2245. (IF=7.3，中科院2区，第一作者)
6. Wang YY, Xu YB, Xu SL, et al. Bacillus subtilis DSM29784 Alleviates Negative Effects on Growth Performance in Broilers by Improving the Intestinal Health Under Necrotic Enteritis Challenge. Frontiers in Microbiology, 2021, 12: 723187. (IF=5.2，中科院2区，第一作者)
7. Zhou YH, Wang YY (Co-first author), Huang YL, et al. Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Nanovesicles Alleviated Colitis via Modulating Th17/Treg Balance Through Hsa-miR-27b-3p-Mediated Suppression of PI3K/AKT/STAT3 Signaling Pathway. International Journal of Nanomedicine, 2025, 20: 15683-15704. (IF=7.7，中科院2区，Top期刊，共同第一作者)
8. Xu YB, Wang YY, Ding XQ, et al. Inhibitory effects of reuterin on biofilm formation, quorum sensing and virulence genes of Clostridium perfringens. LWT-Food Science and Technology, 2022, 162: 113489. (IF=6.9，中科院1区，Top期刊，第二作者)
9. Wang YY, Heng CN, Zhou XH, et al. Supplemental Bacillus subtilis DSM 29784 and enzymes, alone or in combination, as alternatives for antibiotics to improve growth performance, digestive enzyme activity, anti-oxidative status, immune response and the intestinal barrier of broiler chickens. British Journal of Nutrition, 2021, 125: 494-507. (IF=4.125，中科院2区，第一作者)
10. Wang YY, Wang DC, Wang JS, et al. Effects of different stocking densities on tracheal barrier function and its metabolic changes in finishing broilers. Poultry Science, 2020, 99: 6307-6316. (IF=4.5，中科院2区，Top期刊，第一作者)
11. Wang YY, Xia L, Guo TY, et al. Metabolic changes and physiological responses of broilers in the final stage of growth exposed to different environmental temperatures. Poultry Science, 2020, 99: 2017-2025. (IF=4.5，中科院2区，Top期刊，第一作者)
12. Wang YY, Wang YB, Xu H, et al. Direct-fed glucose oxidase and its combination with SC06 on growth performance, meat quality, intestinal barrier, antioxidative status, and immunity of yellow-feathered broilers. Poultry Science, 2018, 97:3540-3549 (IF=4.5，中科院2区，Top期刊，第一作者)
13. Li YL, Wang YY (Co-first author), Wu YP, et al. Echinacea purpurea extracts promote murine dendritic cell maturation by activation of JNK, p38 MAPK and NF-κB pathways. Developmental and Comparative Immunology, 2017, 73: 21-26. (IF=2.7，中科院3区，共同第一作者)
发明专利：
一种罗伊氏黏液乳杆菌LR21及其应用（授权专利）
一种pH响应型W1/O/W2型乳液及其制备方法（授权专利）
一种鸡肠类器官与免疫细胞共培养模型的构建方法（受理专利）
金银花来源的外泌体在制备预防、改善或治疗炎症性肠病产品中的应用（受理专利）
